Acetate → 2-[3,5-Bis(trifluoromethyl)phenyl]-1H-indene

HRID 2321478Notes

Reaction equation

[CH2:1]1[CH:2]=[CH:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]21.[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40].[I:10][c:11]1[cH:12][c:13]([C:21]([F:22])([F:23])[F:24])[cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]1.[O-:26][C:27]([CH3:28])=[O:29].[O-:30][C:31]([CH3:32])=[O:33].[Pd+2:25]>>[CH:1]1=[C:2]([c:11]2[cH:12][c:13]([C:21]([F:22])([F:23])[F:24])[cH:14][c:15]([C:17]([F:18])([F:19])[F:20])[cH:16]2)[CH2:3][c:4]2[cH:5][cH:6][cH:7][cH:8][c:9]21

Participants

Reactant 5

HCID 175Acetate2×

HCID 7219Indene

HCID 8471Triethylamine

HCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)

HCID 6309701-Iodo-3,5-bis(trifluoromethyl)benzene

Product 1

HCID 120106252-[3,5-Bis(trifluoromethyl)phenyl]-1H-indene

Sources & evidence

ORD record: ord-56655b02311649e1b12eaec9da9e731d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (10/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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