Hydrochloric Acid → 2-{4-[(4'-{[4-(Methoxymethyl)piperidin-1-yl]carbonyl}-2'-methylbiphenyl-3-yl)methoxy]benzyl}-1,2,4-oxadiazolidine-3,5-dione

HRID 2321771Notes

Reaction equation

HRID 2321771 reaction equation
[CH3:34][O:35][CH2:36][CH:37]1[CH2:38][CH2:39][NH:40][CH2:41][CH2:42]1.[CH3:43][CH2:44][N:45]([CH2:46][CH3:47])[CH2:48][CH3:49].[CH:50]([Cl:51])([Cl:52])[Cl:53].[ClH:33].[O:1]=[c:2]1[n:3]([CH2:8][c:9]2[cH:10][cH:11][c:12]([O:13][CH2:14][c:15]3[cH:16][c:17](-[c:21]4[c:22]([CH3:30])[cH:23][c:24]([C:27](=[O:28])[OH:29])[cH:25][cH:26]4)[cH:18][cH:19][cH:20]3)[cH:31][cH:32]2)[o:4][c:5](=[O:7])[nH:6]1>>[O:1]=[c:2]1[n:3]([CH2:8][c:9]2[cH:10][cH:11][c:12]([O:13][CH2:14][c:15]3[cH:16][c:17](-[c:21]4[c:22]([CH3:30])[cH:23][c:24]([C:27](=[O:28])[N:40]5[CH2:39][CH2:38][CH:37]([CH2:36][O:35][CH3:34])[CH2:42][CH2:41]5)[cH:25][cH:26]4)[cH:18][cH:19][cH:20]3)[cH:31][cH:32]2)[o:4][c:5](=[O:7])[nH:6]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6212ChloroformHCID 8471TriethylamineHCID 47152834-(Methoxymethyl)piperidineHCID 577873303'-({4-[(3,5-Dioxo-1,2,4-oxadiazolidin-2-yl)methyl]phenoxy}methyl)-2-methylbiphenyl-4-carboxylic acid

Product 1

HCID 577879242-{4-[(4'-{[4-(Methoxymethyl)piperidin-1-yl]carbonyl}-2'-methylbiphenyl-3-yl)methoxy]benzyl}-1,2,4-oxadiazolidine-3,5-dione

Sources & evidence

ORD record
ord-437e8cbf462b43808c6a710bc4a3f4db
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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