Dimethylformamide → 1-Acetyl-piperidine-4-carboxylic acid {3-[5-(2-bromo-3-methyl-benzoyl)-hexahydro-pyrrolo[3,4-c]pyrrol-2-yl]-propyl}-(3-chloro-4-methyl-phenyl)-amide
Reaction equation
[Br:1][c:2]1[c:3]([C:4](=[O:5])[OH:6])[cH:7][cH:8][cH:9][c:10]1[CH3:11].[CH:56]([N:57]([CH2:58][CH3:59])[CH:60]([CH3:61])[CH3:62])([CH3:63])[CH3:64].[Cl:25][c:26]1[cH:27][c:28]([N:33]([C:34](=[O:35])[CH:36]2[CH2:37][CH2:38][N:39]([C:42]([CH3:43])=[O:44])[CH2:40][CH2:41]2)[CH2:45][CH2:46][CH2:47][N:48]2[CH2:49][CH:50]3[CH2:51][NH:52][CH2:53][CH:54]3[CH2:55]2)[cH:29][cH:30][c:31]1[CH3:32].[Cl:65][CH2:66][Cl:67].[NH:12]=[C:13]=[NH:14].[O:68]=[CH:69][N:70]([CH3:71])[CH3:72].[OH:15][n:16]1[c:17]2[c:18]([cH:19][cH:20][cH:21][cH:22]2)[n:23][n:24]1>>[Br:1][c:2]1[c:3]([C:4](=[O:6])[N:52]2[CH2:51][CH:50]3[CH2:49][N:48]([CH2:47][CH2:46][CH2:45][N:33]([c:28]4[cH:27][c:26]([Cl:25])[c:31]([CH3:32])[cH:30][cH:29]4)[C:34](=[O:35])[CH:36]4[CH2:37][CH2:38][N:39]([C:42]([CH3:43])=[O:44])[CH2:40][CH2:41]4)[CH2:55][CH:54]3[CH2:53]2)[cH:7][cH:8][cH:9][c:10]1[CH3:11]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-4e66572fd4d34a1791399086ab96c49c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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