Bromide ion → methyl 10-[(1-benzylpyrrolidin-2-yl)methoxy]-19-cyclohexyl-8-oxa-12-azatetracyclo[10.7.0.02,7.013,18]nonadeca-1(19),2,4,6,13(18),14,16-heptaene-15-carboxylate
Reaction equation
[Br-:55].[CH2:34]([c:35]1[cH:36][cH:37][cH:38][cH:39][cH:40]1)[NH+:41]1[CH:42]([CH2:46][Cl:47])[CH2:43][CH2:44][CH2:45]1.[CH3:48][c:49]1[cH:50][cH:51][cH:52][cH:53][cH:54]1.[CH3:56][CH2:57][CH2:58][CH2:59][N+:60]([CH2:61][CH2:62][CH2:63][CH3:64])([CH2:65][CH2:66][CH2:67][CH3:68])[CH2:69][CH2:70][CH2:71][CH3:72].[CH3:73][CH2:74][O:75][C:76]([CH3:77])=[O:78].[CH:1]1([c:7]2[c:8]3[cH:9][cH:10][c:11]([C:27](=[O:28])[O:29][CH3:30])[cH:12][c:13]3[n:14]3[c:21]2-[c:20]2[c:19]([cH:25][cH:24][cH:23][cH:22]2)[O:18][CH2:17][CH:16]([OH:26])[CH2:15]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1.[Cl-:33].[Na+:32].[OH-:31]>>[CH:1]1([c:7]2[c:8]3[cH:9][cH:10][c:11]([C:27](=[O:28])[O:29][CH3:30])[cH:12][c:13]3[n:14]3[c:21]2-[c:20]2[c:19]([cH:25][cH:24][cH:23][cH:22]2)[O:18][CH2:17][CH:16]([O:26][CH2:46][CH:42]2[N:41]([CH2:34][c:35]4[cH:36][cH:37][cH:38][cH:39][cH:40]4)[CH2:45][CH2:44][CH2:43]2)[CH2:15]3)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-b2cbf714c1d44c879777635546086b64
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…