Water → tert-Butyl 4-(6-amino-3,5-difluoropyridin-2-yl)piperazine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][c:16]([F:22])[c:17]([F:21])[cH:18][c:19]2[F:20])[CH2:12][CH2:13]1.[C:23]1(=[O:24])[NH:27][C:25](=[O:26])[c:28]2[cH:29][cH:30][cH:31][cH:32][c:33]21.[K:34].[O:35]=[CH:36][N:37]([CH3:38])[CH3:39].[OH2:40]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[n:15][c:16]([NH2:27])[c:17]([F:21])[cH:18][c:19]2[F:20])[CH2:12][CH2:13]1Participants
6
Sources & evidence
- ORD record
- ord-943c0cad3b724fcaa2b69e246f8b1205
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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