1,2-Dichloroethane → 1-((2-Chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)piperidin-4-ol

HRID 2322932Notes

Reaction equation

HRID 2322932 reaction equation
[C:26]([OH:27])(=[O:28])[CH3:29].[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([CH:11]=[O:12])[cH:10]2.[Cl:30][CH2:31][CH2:32][Cl:33].[NH:19]1[CH2:20][CH2:21][CH:22]([OH:25])[CH2:23][CH2:24]1>>[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[s:8][c:9]([CH2:11][N:19]1[CH2:20][CH2:21][CH:22]([OH:25])[CH2:23][CH2:24]1)[cH:10]2

Participants

5

Reactant 4

HCID 111,2-DichloroethaneHCID 176Acetic AcidHCID 79341Piperidin-4-olHCID 568338442-Chloro-4-morpholinothieno[2,3-d]pyrimidine-6-carbaldehyde

Product 1

HCID 582339121-((2-Chloro-4-morpholinothieno[2,3-d]pyrimidin-6-yl)methyl)piperidin-4-ol

Sources & evidence

ORD record
ord-18c8d1fe66c74385a2883f13d9e1c6d8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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