Water → tert-butyl 6,6-difluoro-1-(1-methyl-4-nitro-1H-pyrazol-5-yl)azepan-4-yl(methyl)carbamate
Reaction equation
[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH3:27][Si:28]([CH3:29])([CH3:30])[N-:31][Si:32]([CH3:33])([CH3:34])[CH3:35].[F:1][C:2]1([F:26])[CH2:3][CH:4]([NH:18][C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[CH2:5][CH2:6][N:7]([c:9]2[c:10]([N+:15](=[O:16])[O-:17])[cH:11][n:12][n:13]2[CH3:14])[CH2:8]1.[I:37][CH3:38].[Li+:36].[OH2:39]>>[F:1][C:2]1([F:26])[CH2:3][CH:4]([N:18]([C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[CH3:27])[CH2:5][CH2:6][N:7]([c:9]2[c:10]([N+:15](=[O:16])[O-:17])[cH:11][n:12][n:13]2[CH3:14])[CH2:8]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-ffa0e3daa4c740b19d4f12a5bf8a7055
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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