Dimethylformamide → 3-{[[(3-Bromo-4-fluorophenyl)methyl](methyl)amino]methyl}-N-{[1,6-diethyl-4-(tetrahydro-2H-pyran-4-ylamino)-1H-pyrazolo[3,4-b]pyridin-5-yl]methyl}benzamide
Reaction equation
[Br:33][c:34]1[cH:35][c:36]([CH2:41][NH:42][CH3:43])[cH:37][cH:38][c:39]1[F:40].[CH3:44][CH2:45][O:46][C:47]([CH3:48])=[O:49].[Cl:1][CH2:2][c:3]1[cH:4][c:5]([C:6](=[O:7])[NH:8][CH2:9][c:10]2[c:11]([NH:23][CH:24]3[CH2:25][CH2:26][O:27][CH2:28][CH2:29]3)[c:12]3[c:13]([n:14][c:15]2[CH2:16][CH3:17])[n:18]([CH2:21][CH3:22])[n:19][cH:20]3)[cH:30][cH:31][cH:32]1.[O:50]=[CH:51][N:52]([CH3:53])[CH3:54]>>[CH2:2]([c:3]1[cH:4][c:5]([C:6](=[O:7])[NH:8][CH2:9][c:10]2[c:11]([NH:23][CH:24]3[CH2:25][CH2:26][O:27][CH2:28][CH2:29]3)[c:12]3[c:13]([n:14][c:15]2[CH2:16][CH3:17])[n:18]([CH2:21][CH3:22])[n:19][cH:20]3)[cH:30][cH:31][cH:32]1)[N:42]([CH2:41][c:36]1[cH:35][c:34]([Br:33])[c:39]([F:40])[cH:38][cH:37]1)[CH3:43]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-5bfcfaca876149a08a9995b2cec9d71c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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