1-Butanol → Tert-butyl (6-fluoro-4-(2-(5-fluoro-2-(2-(2-oxo-2,3-dihydro-1H-imidazol-1-yl)ethylamino)pyrimidin-4-yl)benzo[b]thiophen-7-yl)pyridin-3-yl)methyl(methyl)carbamate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH3:8])[CH2:9][c:10]1[cH:11][n:12][c:13]([F:33])[cH:14][c:15]1-[c:16]1[cH:17][cH:18][cH:19][c:20]2[c:21]1[s:22][c:23](-[c:25]1[n:26][c:27]([Cl:32])[n:28][cH:29][c:30]1[F:31])[cH:24]2)=[O:34].[CH2:58]([OH:59])[CH2:60][CH2:61][CH3:62].[CH3:35][CH2:36][N:37]([CH2:38][CH3:39])[CH2:40][CH3:41].[F:51][C:52]([F:53])([F:54])[C:55]([OH:56])=[O:57].[NH2:42][CH2:43][CH2:44][n:45]1[c:46](=[O:50])[nH:47][cH:48][cH:49]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([N:7]([CH3:8])[CH2:9][c:10]1[cH:11][n:12][c:13]([F:33])[cH:14][c:15]1-[c:16]1[cH:17][cH:18][cH:19][c:20]2[c:21]1[s:22][c:23](-[c:25]1[n:26][c:27]([NH:42][CH2:43][CH2:44][n:45]3[c:46](=[O:50])[nH:47][cH:48][cH:49]3)[n:28][cH:29][c:30]1[F:31])[cH:24]2)=[O:34]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-c3e17abc23684f79a137a71d1665b917
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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