Hydrochloric Acid → 2-chloro-N-(1-(2,3-dihydroxypropyl)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)-6H-thieno(2,3-b)pyrrole-5-carboxamide

HRID 2323222Notes

Reaction equation

HRID 2323222 reaction equation
[CH2:33]1[O:34][CH2:35][CH2:36][CH2:37]1.[CH3:2][C:3]1([CH3:32])[O:4][CH2:5][CH:6]([CH2:8][N:9]2[C:10](=[O:31])[CH:11]([NH:19][C:20](=[O:21])[c:22]3[cH:23][c:24]4[c:25]([nH:26]3)[s:27][c:28]([Cl:30])[cH:29]4)[CH2:12][c:13]3[cH:14][cH:15][cH:16][cH:17][c:18]32)[O:7]1.[ClH:1]>>[OH:4][CH2:5][CH:6]([OH:7])[CH2:8][N:9]1[C:10](=[O:31])[CH:11]([NH:19][C:20](=[O:21])[c:22]2[cH:23][c:24]3[c:25]([nH:26]2)[s:27][c:28]([Cl:30])[cH:29]3)[CH2:12][c:13]2[cH:14][cH:15][cH:16][cH:17][c:18]21

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 8028TetrahydrofuranHCID 21906856N-[1-(2,2-Dimethyl-1,3-dioxolan-4-ylmethyl)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl]-2-chloro-6H-thieno[2,3-b]pyrrole-5-carboxamide

Product 1

HCID 117428502-chloro-N-(1-(2,3-dihydroxypropyl)-2-oxo-1,2,3,4-tetrahydroquinolin-3-yl)-6H-thieno(2,3-b)pyrrole-5-carboxamide

Sources & evidence

ORD record
ord-73d4d3131e134d3494f9b6927e85196b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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