Acetonitrile → 6-[3-(6-chloro-3,4-dihydro-2H-quinolin-1-yl)-2-oxopyrrolidin-1-yl]-N-(1,3-thiazol-2-yl)pyridine-3-sulfonamide
Reaction equation
[CH2:1]([CH:2]=[CH2:3])[N:4]([S:5](=[O:6])(=[O:7])[c:8]1[cH:9][n:10][c:11]([N:14]2[C:15](=[O:30])[CH:16]([N:19]3[CH2:20][CH2:21][CH2:22][c:23]4[cH:24][c:25]([Cl:29])[cH:26][cH:27][c:28]43)[CH2:17][CH2:18]2)[cH:12][cH:13]1)[c:31]1[s:32][cH:33][cH:34][n:35]1.[CH3:124][C:125]#[N:126].[CH3:36][N:37]1[C:38](=[O:39])[CH2:40][C:41](=[O:42])[N:43]([CH3:44])[C:45]1=[O:46].[Pd:123].[c:104]1([P:105]([c:106]2[cH:107][cH:108][cH:109][cH:110][cH:111]2)[c:112]2[cH:113][cH:114][cH:115][cH:116][cH:117]2)[cH:118][cH:119][cH:120][cH:121][cH:122]1.[c:47]1([P:48]([c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[c:55]2[cH:56][cH:57][cH:58][cH:59][cH:60]2)[cH:61][cH:62][cH:63][cH:64][cH:65]1.[c:66]1([P:67]([c:68]2[cH:69][cH:70][cH:71][cH:72][cH:73]2)[c:74]2[cH:75][cH:76][cH:77][cH:78][cH:79]2)[cH:80][cH:81][cH:82][cH:83][cH:84]1.[c:85]1([P:86]([c:87]2[cH:88][cH:89][cH:90][cH:91][cH:92]2)[c:93]2[cH:94][cH:95][cH:96][cH:97][cH:98]2)[cH:99][cH:100][cH:101][cH:102][cH:103]1>>[NH:4]([S:5](=[O:6])(=[O:7])[c:8]1[cH:9][n:10][c:11]([N:14]2[C:15](=[O:30])[CH:16]([N:19]3[CH2:20][CH2:21][CH2:22][c:23]4[cH:24][c:25]([Cl:29])[cH:26][cH:27][c:28]43)[CH2:17][CH2:18]2)[cH:12][cH:13]1)[c:31]1[s:32][cH:33][cH:34][n:35]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-574eb8c5bbf44321ba66f6ab2a1f8a6b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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