Potassium Cation → tert-butyl 5-(7-methoxy-6-(2-methoxyethoxy)-2-(3-(nicotinamido)phenyl)quinazolin-4-ylamino)-1H-indazole-1-carboxylate

HRID 2323471Notes

Reaction equation

HRID 2323471 reaction equation
[Br:46][CH2:47][CH2:48][O:49][CH3:50].[K+:51].[K+:52].[O-:53][C:54]([O-:55])=[O:56].[O:57]=[CH:58][N:59]([CH3:60])[CH3:61].[OH:1][c:2]1[cH:3][c:4]2[c:5]([NH:29][c:30]3[cH:31][c:32]4[cH:33][n:34][n:35]([C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[c:36]4[cH:37][cH:38]3)[n:6][c:7](-[c:14]3[cH:15][c:16]([NH:20][C:21]([c:22]4[cH:23][n:24][cH:25][cH:26][cH:27]4)=[O:28])[cH:17][cH:18][cH:19]3)[n:8][c:9]2[cH:10][c:11]1[O:12][CH3:13]>>[O:1]([c:2]1[cH:3][c:4]2[c:5]([NH:29][c:30]3[cH:31][c:32]4[cH:33][n:34][n:35]([C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[c:36]4[cH:37][cH:38]3)[n:6][c:7](-[c:14]3[cH:15][c:16]([NH:20][C:21]([c:22]4[cH:23][n:24][cH:25][cH:26][cH:27]4)=[O:28])[cH:17][cH:18][cH:19]3)[n:8][c:9]2[cH:10][c:11]1[O:12][CH3:13])[CH2:47][CH2:48][O:49][CH3:50]

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 809722-Bromoethyl methyl etherHCID 68789688HCID 68789688, compound

Product 1

HCID 59361913tert-butyl 5-(7-methoxy-6-(2-methoxyethoxy)-2-(3-(nicotinamido)phenyl)quinazolin-4-ylamino)-1H-indazole-1-carboxylate

Sources & evidence

ORD record
ord-40c67507d2d244b2b5d88ddb1b9ee9e5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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