Ethyl Acetate → N-(3-Fluoro-4-methanesulfonylamino-benzyl)-3-(6-pyrrolidin-1-yl-pyridin-3-yl)-acrylamide

HRID 2323677Notes

Reaction equation

HRID 2323677 reaction equation
[CH2:26]1[CH2:27][CH2:28][NH:29][CH2:30]1.[CH3:31][CH2:32][O:33][C:34]([CH3:35])=[O:36].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]=[CH:9][C:10](=[O:11])[NH:12][CH2:13][c:14]2[cH:15][c:16]([F:25])[c:17]([NH:20][S:21](=[O:22])(=[O:23])[CH3:24])[cH:18][cH:19]2)[cH:6][n:7]1>>[c:2]1([N:29]2[CH2:28][CH2:27][CH2:26][CH2:30]2)[cH:3][cH:4][c:5]([CH:8]=[CH:9][C:10](=[O:11])[NH:12][CH2:13][c:14]2[cH:15][c:16]([F:25])[c:17]([NH:20][S:21](=[O:22])(=[O:23])[CH3:24])[cH:18][cH:19]2)[cH:6][n:7]1

Participants

4

Reactant 3

HCID 8857Ethyl AcetateHCID 31268PyrrolidineHCID 723356623-(6-Chloro-pyridin-3-yl)-N-(3-fluoro-4-methane sulfonylamino-benzyl)-acrylamide

Product 1

HCID 68786118N-(3-Fluoro-4-methanesulfonylamino-benzyl)-3-(6-pyrrolidin-1-yl-pyridin-3-yl)-acrylamide

Sources & evidence

ORD record
ord-370f041fb4df4563865e4045ebefa849
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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