Dimethyl Sulfoxide → N~2~-(4-Fluorobenzene-1-sulfonyl)-N-(4-methyl-1-oxopentan-2-yl)valinamide

HRID 2323788Notes

Reaction equation

HRID 2323788 reaction equation
[CH3:26][CH2:27][N:28]([CH2:29][CH3:30])[CH2:31][CH3:32].[CH3:43][CH2:44][O:45][C:46](=[O:47])[CH3:48].[CH3:49][S:50](=[O:51])[CH3:52].[Cl:53][CH2:54][Cl:55].[F:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[NH:11][CH:12]([CH:13]([CH3:14])[CH3:15])[C:16](=[O:17])[NH:18][CH:19]([CH2:20][CH:21]([CH3:22])[CH3:23])[CH2:24][OH:25])[cH:6][cH:7]1.[S:39](=[O:40])(=[O:41])=[O:42].[n:33]1[cH:34][cH:35][cH:36][cH:37][cH:38]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([S:8](=[O:9])(=[O:10])[NH:11][CH:12]([CH:13]([CH3:14])[CH3:15])[C:16](=[O:17])[NH:18][CH:19]([CH2:20][CH:21]([CH3:22])[CH3:23])[CH:24]=[O:25])[cH:6][cH:7]1

Participants

8

Reactant 7

HCID 679Dimethyl SulfoxideHCID 1049PyridineHCID 6344DichloromethaneHCID 8471TriethylamineHCID 8857Ethyl AcetateHCID 24682Sulfur trioxideHCID 22221660HCID 22221660, compound

Product 1

HCID 22134166N~2~-(4-Fluorobenzene-1-sulfonyl)-N-(4-methyl-1-oxopentan-2-yl)valinamide

Sources & evidence

ORD record
ord-87b1221c87e2416ba4ed47a4367df305
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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