Dichloromethane → N-cyclopropyl-2,4-difluoro-5-((2-(pyridin-2-ylamino)thiazol-5-yl)methylamino)benzamide
Reaction equation
[CH2:30]([SiH:31]([CH2:32][CH3:33])[CH2:34][CH3:35])[CH3:36].[Cl:44][CH2:45][Cl:46].[F:37][C:38]([F:39])([F:40])[C:41]([OH:42])=[O:43].[NH2:15][c:16]1[c:17]([F:29])[cH:18][c:19]([F:28])[c:20]([C:21](=[O:22])[NH:23][CH:24]2[CH2:25][CH2:26]2)[cH:27]1.[n:1]1[c:2]([NH:7][c:8]2[s:9][c:10]([CH:13]=[O:14])[cH:11][n:12]2)[cH:3][cH:4][cH:5][cH:6]1>>[n:1]1[c:2]([NH:7][c:8]2[s:9][c:10]([CH2:13][NH:15][c:16]3[c:17]([F:29])[cH:18][c:19]([F:28])[c:20]([C:21](=[O:22])[NH:23][CH:24]4[CH2:25][CH2:26]4)[cH:27]3)[cH:11][n:12]2)[cH:3][cH:4][cH:5][cH:6]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-77ce00e6864048f5a8fa2dd15d22b610
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…