Tetrahydrofuran → Cyclohexanecarboxylic acid, 4-(hydroxymethyl)-, methyl ester

HRID 2324951Notes

Reaction equation

HRID 2324951 reaction equation
[BH4-:27].[BH4-:29].[CH2:22]1[O:23][CH2:24][CH2:25][CH2:26]1.[CH3:1][N:2]([CH3:3])[CH2:4][CH2:5][N:6]([CH3:7])[CH3:8].[CH3:9][O:10][C:11](=[O:12])[CH:13]1[CH2:14][CH2:15][CH:16]([C:19](=[O:20])[Cl:21])[CH2:17][CH2:18]1.[Zn+2:28]>>[CH3:9][O:10][C:11](=[O:12])[CH:13]1[CH2:14][CH2:15][CH:16]([CH2:19][OH:20])[CH2:17][CH2:18]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 8037N,N,N',N'-TetramethylethylenediamineHCID 28123Borohydride2×HCID 32051Zinc(2+)HCID 15380636Methyl 4-(chlorocarbonyl)cyclohexane-1-carboxylate

Product 1

HCID 11073869Cyclohexanecarboxylic acid, 4-(hydroxymethyl)-, methyl ester

Sources & evidence

ORD record
ord-c5f7867435074d3cba6daa1a389fb430
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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