Tetrahydrofuran → methyl 5-amino-4-[7-[[4-(morpholin-4-ylmethyl)furan-2-yl]methoxy]-3-oxo-1H-isoindol-2-yl]-5-oxopentanoate
Reaction equation
[CH2:69]1[O:70][CH2:71][CH2:72][CH2:73]1.[NH2:20][C:21]([CH:22]([CH2:23][CH2:24][C:25](=[O:26])[O:27][CH3:28])[N:29]1[C:30](=[O:39])[c:31]2[cH:32][cH:33][cH:34][c:35]([OH:38])[c:36]2[CH2:37]1)=[O:40].[O:41]=[C:42]([O:43][CH:44]([CH3:45])[CH3:46])[N:47]=[N:48][C:49]([O:50][CH:51]([CH3:52])[CH3:53])=[O:54].[O:55]1[CH2:56][CH2:57][N:58]([CH2:61][c:62]2[cH:63][c:64]([CH2:67][OH:68])[o:65][cH:66]2)[CH2:59][CH2:60]1.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[NH2:20][C:21]([CH:22]([CH2:23][CH2:24][C:25](=[O:26])[O:27][CH3:28])[N:29]1[C:30](=[O:39])[c:31]2[cH:32][cH:33][cH:34][c:35]([O:38][CH2:67][c:64]3[cH:63][c:62]([CH2:61][N:58]4[CH2:57][CH2:56][O:55][CH2:60][CH2:59]4)[cH:66][o:65]3)[c:36]2[CH2:37]1)=[O:40]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-5e07d48ada124f3991d7926612b273ae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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