Methanol → 1-(6-Chloro-5-(2,2,2-trifluoroethoxy)-4'-(trifluoromethyl)biphenyl-3-yl)cyclopentane carboxylic acid
Reaction equation
[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[CH3:36][OH:37].[Cl:1][c:2]1[c:3]([O:28][CH2:29][C:30]([F:31])([F:32])[F:33])[cH:4][c:5]([C:18]2([C:23](=[O:24])[O:25][CH2:26][CH3:27])[CH2:19][CH2:20][CH2:21][CH2:22]2)[cH:6][c:7]1-[c:8]1[cH:9][cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]1.[Li+:35].[OH-:34].[OH2:43]>>[Cl:1][c:2]1[c:3]([O:28][CH2:29][C:30]([F:31])([F:32])[F:33])[cH:4][c:5]([C:18]2([C:23](=[O:24])[OH:25])[CH2:19][CH2:20][CH2:21][CH2:22]2)[cH:6][c:7]1-[c:8]1[cH:9][cH:10][c:11]([C:14]([F:15])([F:16])[F:17])[cH:12][cH:13]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-72618256cc054735a44d8fec67186e50
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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