Tetrahydrofuran → 4-[1-[4-(2-Chloro-1-phenyl-ethoxy)-3-methoxy-phenyl]-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-ethylamino]-benzonitrile
Reaction equation
[Cl:51][CH2:52][CH:53]([OH:54])[c:55]1[cH:56][cH:57][cH:58][cH:59][cH:60]1.[O:1]=[C:2]1[N:3]([CH2:12][CH:13]([c:14]2[cH:15][c:16]([O:21][CH3:22])[c:17]([OH:20])[cH:18][cH:19]2)[NH:23][c:24]2[cH:25][cH:26][c:27]([C:28]#[N:29])[cH:30][cH:31]2)[C:4](=[O:11])[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21.[O:61]1[CH2:62][CH2:63][CH2:64][CH2:65]1.[c:32]1([P:33]([c:34]2[cH:35][cH:36][cH:37][cH:38][cH:39]2)[c:40]2[cH:41][cH:42][cH:43][cH:44][cH:45]2)[cH:46][cH:47][cH:48][cH:49][cH:50]1>>[O:1]=[C:2]1[N:3]([CH2:12][CH:13]([c:14]2[cH:15][c:16]([O:21][CH3:22])[c:17]([O:20][CH:53]([CH2:52][Cl:51])[c:55]3[cH:56][cH:57][cH:58][cH:59][cH:60]3)[cH:18][cH:19]2)[NH:23][c:24]2[cH:25][cH:26][c:27]([C:28]#[N:29])[cH:30][cH:31]2)[C:4](=[O:11])[c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]21Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-3ef25bd7f1e641d387f065e02ce6d126
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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