Pyridine → Methyl 3-(3-(3-(7-bromoimidazo[1,2-a]pyridine-3-carboxamido)-4-methylphenyl)-1,2,4-oxadiazol-5-yl)azetidine-1-carboxylate

HRID 2326540Notes

Reaction equation

HRID 2326540 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[n:5]([cH:6][cH:7]1)[c:8]([C:11](=[O:12])[OH:13])[cH:9][n:10]2.[Cl:14][C:15]([C:16]([Cl:17])=[O:18])=[O:19].[Cl:46][CH2:47][Cl:48].[NH2:25][c:26]1[cH:27][c:28](-[c:33]2[n:34][o:35][c:36]([CH:38]3[CH2:39][N:40]([C:42](=[O:43])[O:44][CH3:45])[CH2:41]3)[n:37]2)[cH:29][cH:30][c:31]1[CH3:32].[O:20]=[CH:21][N:22]([CH3:23])[CH3:24].[cH:49]1[cH:50][cH:51][n:52][cH:53][cH:54]1>>[Br:1][c:2]1[cH:3][c:4]2[n:5]([cH:6][cH:7]1)[c:8]([C:11](=[O:13])[NH:25][c:26]1[cH:27][c:28](-[c:33]3[n:34][o:35][c:36]([CH:38]4[CH2:39][N:40]([C:42](=[O:43])[O:44][CH3:45])[CH2:41]4)[n:37]3)[cH:29][cH:30][c:31]1[CH3:32])[cH:9][n:10]2

Participants

7

Reactant 6

HCID 1049PyridineHCID 6228DimethylformamideHCID 6344DichloromethaneHCID 65578Oxalyl chlorideHCID 672614887-Bromoimidazo[1,2-a]pyridine-3-carboxylic acidHCID 86677444Methyl 3-(3-(3-amino-4-methylphenyl)-1,2,4-oxadiazol-5-yl)azetidine-1-carboxylate

Product 1

HCID 71281208Methyl 3-(3-(3-(7-bromoimidazo[1,2-a]pyridine-3-carboxamido)-4-methylphenyl)-1,2,4-oxadiazol-5-yl)azetidine-1-carboxylate

Sources & evidence

ORD record
ord-01d7017489ab41268f158e223c51074a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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