Hydrochloric Acid → Loratadine

HRID 2326901Notes

Reaction equation

HRID 2326901 reaction equation
[Ba+2:38].[C:34](=[O:35])([O-:36])[O-:37].[CH2:2]([CH3:3])[O:4][C:5](=[O:6])[N:7]1[CH2:8][CH2:9][CH:10]([C:13](=[O:14])[c:15]2[n:16][cH:17][cH:18][cH:19][c:20]2[CH2:21][CH2:22][c:23]2[cH:24][c:25]([Cl:29])[cH:26][cH:27][cH:28]2)[CH2:11][CH2:12]1.[Cl:30][C:31]([O-:32])=[O:33].[ClH:1].[F:39][C:40]([F:41])([F:42])[S:43]([OH:44])(=[O:45])=[O:46].[OH2:47]>>[CH2:2]([CH3:3])[O:4][C:5](=[O:6])[N:7]1[CH2:8][CH2:9][C:10](=[C:13]2[c:15]3[n:16][cH:17][cH:18][cH:19][c:20]3[CH2:21][CH2:22][c:23]3[cH:24][c:25]([Cl:29])[cH:26][cH:27][c:28]32)[CH2:11][CH2:12]1

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 962WaterHCID 19660Carbonate IonHCID 62406Trifluoromethanesulfonic acidHCID 104810Barium ionHCID 198464614-[[3-[2-(3-Chlorophenyl)ethyl]-2-pyridinyl]carbonyl]-1-piperidinecarboxylic AcidHCID 21226386Carbonochloridate

Product 1

HCID 3957Loratadine

Sources & evidence

ORD record
ord-ca35c099babd47d0bc7b1f5227339af6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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