Dimethyl Sulfoxide → 1-Boc-2-Formylpyrrolidine

HRID 2326904Notes

Reaction equation

HRID 2326904 reaction equation
[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[CH:19]([CH2:23][OH:24])[CH2:20][CH2:21][CH2:22]1.[CH3:1][S:2]([CH3:3])=[O:4].[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[Cl:32][CH2:33][Cl:34].[Cl:5][C:6]([C:7]([Cl:8])=[O:9])=[O:10]>>[C:11]([CH3:12])([CH3:13])([CH3:14])[O:15][C:16](=[O:17])[N:18]1[CH:19]([CH:23]=[O:24])[CH2:20][CH2:21][CH2:22]1

Participants

6

Reactant 5

HCID 679Dimethyl SulfoxideHCID 6344DichloromethaneHCID 8471TriethylamineHCID 65578Oxalyl chlorideHCID 550865tert-Butyl 2-(hydroxymethyl)pyrrolidine-1-carboxylate

Product 1

HCID 42278151-Boc-2-Formylpyrrolidine

Sources & evidence

ORD record
ord-303913c3c3234d73b75750b8dffdb2f2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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