Tetrahydrofuran → N-[[6-[(5-cyclopropyl-1H-pyrazol-3-yl)amino]-5-fluoro-2-[1-(4-fluorophenyl)ethylamino]-3-pyridinyl]methyl]-1,1,1-trifluoromethanesulfonamide
Reaction equation
[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:42][N:43]([c:44]1[cH:45][cH:46][n:47][cH:48][cH:49]1)[CH3:50].[F:29][C:30]([S:31](=[O:32])(=[O:33])[Cl:34])([F:35])[F:36].[NH2:1][CH2:2][c:3]1[c:4]([NH:19][CH:20]([CH3:21])[c:22]2[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]2)[n:5][c:6]([NH:10][c:11]2[n:12][nH:13][c:14]([CH:16]3[CH2:17][CH2:18]3)[cH:15]2)[c:7]([F:9])[cH:8]1>>[NH:1]([CH2:2][c:3]1[c:4]([NH:19][CH:20]([CH3:21])[c:22]2[cH:23][cH:24][c:25]([F:28])[cH:26][cH:27]2)[n:5][c:6]([NH:10][c:11]2[n:12][nH:13][c:14]([CH:16]3[CH2:17][CH2:18]3)[cH:15]2)[c:7]([F:9])[cH:8]1)[S:31]([C:30]([F:29])([F:35])[F:36])(=[O:32])=[O:33]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-e0d905e261c84e24ab7820ae761414bc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
Loading…