Tetrahydrofuran → Tert-butyl 2-[4-(2-aminopyrimidin-5-yl)-2-fluorophenoxy]propionate
Reaction equation
[NH2:42][c:43]1[n:44][cH:45][c:46](-[c:49]2[cH:50][c:51]([F:56])[c:52]([OH:55])[cH:53][cH:54]2)[cH:47][n:48]1.[O:20]=[C:21]([O:22][CH2:23][CH3:24])[N:25]=[N:26][C:27]([O:28][CH2:29][CH3:30])=[O:31].[O:57]1[CH2:58][CH2:59][CH2:60][CH2:61]1.[OH:32][CH:33]([C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[CH3:41].[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[O:32]([CH:33]([C:34](=[O:35])[O:36][C:37]([CH3:38])([CH3:39])[CH3:40])[CH3:41])[c:52]1[c:51]([F:56])[cH:50][c:49](-[c:46]2[cH:45][n:44][c:43]([NH2:42])[n:48][cH:47]2)[cH:54][cH:53]1Participants
6
Sources & evidence
- ORD record
- ord-488f25bef5ae4f5ba9ffd3df424c4287
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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