Tetrahydrofuran → 7,8-Difluoro-3,4-dihydro-2H-1,4-benzothiazine
Reaction equation
[Al+3:15].[CH2:20]1[O:21][CH2:22][CH2:23][CH2:24]1.[F:1][c:2]1[c:3]([F:13])[c:4]2[c:5]([cH:11][cH:12]1)[NH:6][C:7](=[O:10])[CH2:8][S:9]2.[H-:14].[H-:17].[H-:18].[H-:19].[Li+:16]>>[F:1][c:2]1[c:3]([F:13])[c:4]2[c:5]([cH:11][cH:12]1)[NH:6][CH2:7][CH2:8][S:9]2Participants
6
Sources & evidence
- ORD record
- ord-28375fb1166849f9b44360957fdeca76
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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