Hydrochloric Acid → (1-{4-Methoxy-6-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-[1,3,5]triazin-2-yl}-piperidin-4-yl)-acetic acid

HRID 2327014Notes

Reaction equation

HRID 2327014 reaction equation
[CH3:12][CH2:13][N:14]([CH2:15][CH3:16])[CH2:17][CH3:18].[CH3:43][OH:44].[Cl:19][c:20]1[n:21][c:22]([NH:28][c:29]2[cH:30][c:31]([O:41][CH3:42])[c:32](-[n:35]3[cH:36][n:37][c:38]([CH3:40])[cH:39]3)[cH:33][cH:34]2)[n:23][c:24]([O:26][CH3:27])[n:25]1.[ClH:1].[NH:2]1[CH2:3][CH2:4][CH:5]([CH2:8][C:9](=[O:10])[OH:11])[CH2:6][CH2:7]1>>[N:2]1([c:20]2[n:21][c:22]([NH:28][c:29]3[cH:30][c:31]([O:41][CH3:42])[c:32](-[n:35]4[cH:36][n:37][c:38]([CH3:40])[cH:39]4)[cH:33][cH:34]3)[n:23][c:24]([O:26][CH3:27])[n:25]2)[CH2:3][CH2:4][CH:5]([CH2:8][C:9](=[O:10])[OH:11])[CH2:6][CH2:7]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 887MethanolHCID 8471TriethylamineHCID 15125944-Piperidineacetic acidHCID 86640783(4-Chloro-6-methoxy-[1,3,5]triazin-2-yl)-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenyl]-amine

Product 1

HCID 45274965(1-{4-Methoxy-6-[3-methoxy-4-(4-methyl-imidazol-1-yl)-phenylamino]-[1,3,5]triazin-2-yl}-piperidin-4-yl)-acetic acid

Sources & evidence

ORD record
ord-4276288aebb849d7a26321a561924f12
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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