Tetrahydrofuran → 1-(2-(1-Methylpyrrolidin-2-yl)ethyl)-2,3,4,5-tetrahydro-1H-benzo[b]azepin-7-amine
Reaction equation
[Al+3:23].[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[H-:22].[H-:25].[H-:26].[H-:27].[Li+:24].[NH2:1][c:2]1[cH:3][c:4]2[c:5]([cH:20][cH:21]1)[N:6]([CH2:12][CH2:13][CH:14]1[N:15]([CH3:19])[CH2:16][CH2:17][CH2:18]1)[C:7](=[O:11])[CH2:8][CH2:9][CH2:10]2>>[NH2:1][c:2]1[cH:3][c:4]2[c:5]([cH:20][cH:21]1)[N:6]([CH2:12][CH2:13][CH:14]1[N:15]([CH3:19])[CH2:16][CH2:17][CH2:18]1)[CH2:7][CH2:8][CH2:9][CH2:10]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-6273bdccfd444dd198fcd98cdb304a8c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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