Hydrochloric Acid → 4-(1-Amino-1-phenyl-ethyl)-cyclohexanol

HRID 2327149Notes

Reaction equation

HRID 2327149 reaction equation
[C:8]([O:9][C:10](=[O:11])[NH:14][C:15]([CH3:16])([c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)[CH:23]1[CH2:24][CH2:25][CH:26]([OH:29])[CH2:27][CH2:28]1)([CH3:12])([CH3:13])[CH3:30].[CH3:36][C:37]#[N:38].[Cl:33][CH2:34][Cl:35].[ClH:31].[OH2:32].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[NH2:14][C:15]([CH3:16])([c:17]1[cH:18][cH:19][cH:20][cH:21][cH:22]1)[CH:23]1[CH2:24][CH2:25][CH:26]([OH:29])[CH2:27][CH2:28]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 962WaterHCID 6342AcetonitrileHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 70252586[1-(4-Hydroxy-cyclohexyl)-1-phenyl-ethyl]carbamic acid tert-butyl ester

Product 1

HCID 583809984-(1-Amino-1-phenyl-ethyl)-cyclohexanol

Sources & evidence

ORD record
ord-8f2d6578695c4f67854e5f7b4f501cab
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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