Chloride → Tert-butyl 2-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-yl)acetate
Reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5](=[O:13])[n:6]([CH3:12])[cH:7][n:8][c:9]2[cH:10][cH:11]1.[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20]([CH2:21][Zn+:22])=[O:23].[CH2:29]1[O:30][CH2:31][CH2:32][CH2:33]1.[CH3:24][CH2:25][O:26][CH2:27][CH3:28].[Cl-:14].[O:36]=[C:37]([CH:38]=[CH:39][c:40]1[cH:41][cH:42][cH:43][cH:44][cH:45]1)[CH:46]=[CH:47][c:48]1[cH:49][cH:50][cH:51][cH:52][cH:53]1.[O:54]=[C:55]([CH:56]=[CH:57][c:58]1[cH:59][cH:60][cH:61][cH:62][cH:63]1)[CH:64]=[CH:65][c:66]1[cH:67][cH:68][cH:69][cH:70][cH:71]1.[O:72]=[C:73]([CH:74]=[CH:75][c:76]1[cH:77][cH:78][cH:79][cH:80][cH:81]1)[CH:82]=[CH:83][c:84]1[cH:85][cH:86][cH:87][cH:88][cH:89]1.[Pd:34].[Pd:35]>>[c:2]1([CH2:21][C:20]([O:19][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:23])[cH:3][c:4]2[c:5](=[O:13])[n:6]([CH3:12])[cH:7][n:8][c:9]2[cH:10][cH:11]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-273b6143eee74cb4a7de609fc387c4e4
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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