Water → 1-(1-Trityl-1H-imidazol-4-yl)propane-1,3-diol

HRID 2327701Notes

Reaction equation

HRID 2327701 reaction equation
[Al+3:2].[CH2:40]1[O:41][CH2:42][CH2:43][CH2:44]1.[CH2:45]1[O:46][CH2:47][CH2:48][CH2:49]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[OH2:39].[OH:7][CH:8]([CH2:9][C:10](=[O:11])[O:12][CH2:13][CH3:14])[c:15]1[n:16][cH:17][n:18]([C:20]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[cH:19]1>>[OH:7][CH:8]([CH2:9][CH2:10][OH:11])[c:15]1[n:16][cH:17][n:18]([C:20]([c:21]2[cH:22][cH:23][cH:24][cH:25][cH:26]2)([c:27]2[cH:28][cH:29][cH:30][cH:31][cH:32]2)[c:33]2[cH:34][cH:35][cH:36][cH:37][cH:38]2)[cH:19]1

Participants

7

Reactant 6

HCID 962WaterHCID 8028Tetrahydrofuran2×HCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 21879633Ethyl 3-hydroxy-3-(1-trityl-1h-imidazol-4-yl)propanoate

Product 1

HCID 218796071-(1-Trityl-1H-imidazol-4-yl)propane-1,3-diol

Sources & evidence

ORD record
ord-4365e6105cae4e02be26c52897576a9f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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