Chloride → 2-(5-Ethoxy-3-oxo-1,2-dihydroinden-2-yl)isoindole-1,3-dione

HRID 2327798Notes

Reaction equation

HRID 2327798 reaction equation
[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][cH:6][c:7]([CH2:10][CH:11]([C:12](=[O:13])[OH:14])[N:15]2[C:16](=[O:25])[c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]3[C:23]2=[O:24])[cH:8][cH:9]1.[CH2:40]([Cl:41])[Cl:42].[Cl-:39].[F:26][C:27]([F:28])([F:29])[C:30]([O:31][C:32](=[O:33])[C:34]([F:35])([F:36])[F:37])=[O:38]>>[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][cH:6][c:7]2[c:8]([cH:9]1)[C:12](=[O:14])[CH:11]([N:15]1[C:16](=[O:25])[c:17]3[cH:18][cH:19][cH:20][cH:21][c:22]3[C:23]1=[O:24])[CH2:10]2

Participants

5

Reactant 4

HCID 312ChlorideHCID 6344DichloromethaneHCID 9845Trifluoroacetic anhydrideHCID 18519075(S)-2-(1,3-Dioxoisoindolin-2-yl)-3-(4-ethoxyphenyl)propanoic acid

Product 1

HCID 185190722-(5-Ethoxy-3-oxo-1,2-dihydroinden-2-yl)isoindole-1,3-dione

Sources & evidence

ORD record
ord-00c2e8be8a2746f38b8c874c75ee45e4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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