Methyl iodide → 2-[3-(Tert-butyldimethylsilanyloxy)-4,4,4-trifluoro 1-methylbutyl]pyridine
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]([CH2:8][CH2:9][c:10]1[n:11][cH:12][cH:13][cH:14][cH:15]1)[C:16]([F:17])([F:18])[F:19])([CH3:20])[CH3:21].[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:23][CH:24]([N-:25][CH:26]([CH3:27])[CH3:28])[CH3:29].[CH3:30][I:31].[Li+:22]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[Si:5]([O:6][CH:7]([CH2:8][CH:9]([c:10]1[n:11][cH:12][cH:13][cH:14][cH:15]1)[CH3:23])[C:16]([F:17])([F:18])[F:19])([CH3:20])[CH3:21]Participants
6
Sources & evidence
- ORD record
- ord-38861209e5de463183767e4ed790d485
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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