Tetrahydrofuran → N-(5-bromo-2-methylphenyl)-4-[(4-phenylquinazolin-2-yl)amino]benzamide

HRID 2328405Notes

Reaction equation

HRID 2328405 reaction equation
[Br:36][c:37]1[cH:38][cH:39][c:40]([CH3:44])[c:41]([NH2:42])[cH:43]1.[CH:27]([N:28]([CH2:29][CH3:30])[CH:31]([CH3:32])[CH3:33])([CH3:34])[CH3:35].[O:45]1[CH2:46][CH2:47][CH2:48][CH2:49]1.[c:1]1(-[c:7]2[n:8][c:9]([NH:17][c:18]3[cH:19][cH:20][c:21]([C:22](=[O:23])[Cl:24])[cH:25][cH:26]3)[n:10][c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]23)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[n:8][c:9]([NH:17][c:18]3[cH:19][cH:20][c:21]([C:22](=[O:23])[NH:42][c:41]4[c:40]([CH3:44])[cH:39][cH:38][c:37]([Br:36])[cH:43]4)[cH:25][cH:26]3)[n:10][c:11]3[cH:12][cH:13][cH:14][cH:15][c:16]23)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 81531DiisopropylethylamineHCID 27348055-Bromo-o-toluidineHCID 576629364-(4-Phenylquinazolin-2-ylamino)benzoyl chloride

Product 1

HCID 57662893N-(5-bromo-2-methylphenyl)-4-[(4-phenylquinazolin-2-yl)amino]benzamide

Sources & evidence

ORD record
ord-6edb51369f7b4c84a667bbd510256a0d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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