Dichloromethane → 1-Oxa-8-azaspiro[4.5]decane-8-carboxylic acid, 4-hydroxy-, 1,1-diMethylethyl ester

HRID 2329581Notes

Reaction equation

HRID 2329581 reaction equation
[CH3:31][CH2:32][N:33]([CH2:34][CH3:35])[CH2:36][CH3:37].[Cl:38][CH2:39][Cl:40].[OH:1][CH:2]([CH2:3][CH2:4][OH:5])[C:6]1([OH:19])[CH2:7][CH2:8][N:9]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:10][CH2:11]1.[c:20]1([CH3:21])[cH:22][cH:23][c:24]([S:25]([Cl:26])(=[O:27])=[O:28])[cH:29][cH:30]1>>[OH:1][CH:2]1[CH2:3][CH2:4][O:19][C:6]12[CH2:7][CH2:8][N:9]([C:12](=[O:13])[O:14][C:15]([CH3:16])([CH3:17])[CH3:18])[CH2:10][CH2:11]2

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 73974-Toluenesulfonyl chlorideHCID 8471TriethylamineHCID 69714411HCID 69714411, compound

Product 1

HCID 697044001-Oxa-8-azaspiro[4.5]decane-8-carboxylic acid, 4-hydroxy-, 1,1-diMethylethyl ester

Sources & evidence

ORD record
ord-1a997969f26c479e8ebfc7fc42628235
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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