Acetone → Tert-butyl [2-(4-fluorophenyl)-4-oxobutyl]methylcarbamate

HRID 2329773Notes

Reaction equation

HRID 2329773 reaction equation
[CH2:51]1[O:52][CH2:53][CH2:54][CH2:55]1.[CH3:22][N+:23]1([O-:24])[CH2:25][CH2:27][O:26][CH2:28][CH2:29]1.[CH3:41][C:42](=[O:43])[CH3:44].[CH3:45][C:46]([OH:47])([CH3:48])[CH3:49].[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][N:10]([C:11]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:17])[CH3:18])[CH2:19][CH:20]=[CH2:21])[cH:6][cH:7]1.[I+3:35]([O-:36])([O-:37])([O-:38])[O-:39].[Na+:34].[Na+:40].[O:56]=[Os:57](=[O:58])(=[O:59])=[O:60].[OH2:50].[S:30](=[O:31])([OH:32])[O-:33]>>[F:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][N:10]([C:11]([O:12][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:17])[CH3:18])[CH2:19][CH:20]=[O:26])[cH:6][cH:7]1

Participants

11

Reactant 10

HCID 180AcetoneHCID 923Sodium ion2×HCID 962WaterHCID 6386tert-ButanolHCID 8028TetrahydrofuranHCID 30318Osmium TetroxideHCID 82029Methyl morpholine oxideHCID 104748BisulfiteHCID 167232PeriodateHCID 86606878Tert-butyl [2-(4-fluorophenyl)pent-4-en-1-yl]methylcarbamate

Product 1

HCID 86606881Tert-butyl [2-(4-fluorophenyl)-4-oxobutyl]methylcarbamate

Sources & evidence

ORD record
ord-aa959fa8e9c24e37b18d15bd35ed46ac
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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