Methane → 5'-Isopropyl-5,2'-dimethoxy-4-trifluoromethyl-biphenyl-2-ylamine
Reaction equation
[C:34].[CH3:32][OH:33].[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][cH:6][c:7]([O:25][CH3:26])[c:8](-[c:10]2[c:11]([N+:22]([O-:23])=[O:24])[cH:12][c:13]([C:18]([F:19])([F:20])[F:21])[c:14]([O:16][CH3:17])[cH:15]2)[cH:9]1.[O:27]1[CH2:28][CH2:29][CH2:30][CH2:31]1.[Pd:35]>>[CH:1]([CH3:2])([CH3:3])[c:4]1[cH:5][cH:6][c:7]([O:25][CH3:26])[c:8](-[c:10]2[c:11]([NH2:22])[cH:12][c:13]([C:18]([F:19])([F:20])[F:21])[c:14]([O:16][CH3:17])[cH:15]2)[cH:9]1Participants
6
Sources & evidence
- ORD record
- ord-65f00695c891468ba19e3678312a91d8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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