Benzyl Alcohol → Methyl 3-(2,2,2-trichloroethoxycarbonylamino)-1-(2,4-dimethoxybenzyl)-4-oxoazetidine-2-carboxylate

HRID 2330489Notes

Reaction equation

HRID 2330489 reaction equation
[C:110]([OH:111])([CH3:112])([CH3:113])[CH3:114].[CH2:79]([O:80][C:81]([NH:82][CH:83]1[C:84](=[O:85])[N:86]([CH2:87][c:88]2[cH:89][cH:90][c:91]([O:92][CH3:93])[cH:94][c:95]2[O:96][CH3:97])[CH:98]1[C:99]([O:100][CH3:101])=[O:102])=[O:103])[c:104]1[cH:105][cH:106][cH:107][cH:108][cH:109]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH2:7][OH:8])[cH:9][cH:10]1.[CH3:46][O:47][c:48]1[c:49]([CH2:50][N:51]2[CH:52]([C:69](=[O:70])[O:71][CH3:72])[CH:53]([NH:56][C:57](=[O:58])[O:59][CH2:60][c:61]3[cH:62][cH:63][c:64]([O:65][CH3:66])[cH:67][cH:68]3)[C:54]2=[O:55])[cH:73][cH:74][c:75]([O:77][CH3:78])[cH:76]1.[NH2:25][CH:26]1[C:27](=[O:28])[N:29]([CH2:30][c:31]2[cH:32][cH:33][c:34]([O:35][CH3:36])[cH:37][c:38]2[O:39][CH3:40])[CH:41]1[C:42]([O:43][CH3:44])=[O:45].[OH:11][CH2:12][c:13]1[cH:14][cH:15][cH:16][cH:17][cH:18]1.[OH:19][CH2:20][C:21]([Cl:22])([Cl:23])[Cl:24]>>[O:19]([CH2:20][C:21]([Cl:22])([Cl:23])[Cl:24])[C:57]([NH:56][CH:53]1[CH:52]([C:69](=[O:70])[O:71][CH3:72])[N:51]([CH2:50][c:49]2[c:48]([O:47][CH3:46])[cH:76][c:75]([O:77][CH3:78])[cH:74][cH:73]2)[C:54]1=[O:55])=[O:58]

Participants

8

Reactant 7

HCID 244Benzyl AlcoholHCID 6386tert-ButanolHCID 77384-Methoxybenzyl alcoholHCID 8259TrichloroethanolHCID 13470810Methyl 3-(benzyloxycarbonylamino)-1-(2,4-dimethoxybenzyl)-4-oxoazetidine-2-carboxylateHCID 14095499Methyl 3-amino-1-[(2,4-dimethoxyphenyl)methyl]-4-oxoazetidine-2-carboxylateHCID 23470086Methyl 3-(p-methoxybenzyloxycarbonylamino)-1-(2,4-dimethoxybenzyl)-4-oxoazetidine-2-carboxylate

Product 1

HCID 14230565Methyl 3-(2,2,2-trichloroethoxycarbonylamino)-1-(2,4-dimethoxybenzyl)-4-oxoazetidine-2-carboxylate

Sources & evidence

ORD record
ord-63d73267b1b84cdfb2dab1424aa3d4a3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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