Allyl bromide → Ethyl 2-[3-(3-chlorophenyl)-2-(4-chlorophenyl)-6-oxo-5-prop-2-enylpiperidin-1-yl]butanoate
Reaction equation
[CH2:30]([CH:31]=[CH2:32])[Br:33].[CH2:44]1[O:45][CH2:46][CH2:47][CH2:48]1.[CH3:34][Si:35]([N-:36][Si:37]([CH3:38])([CH3:39])[CH3:40])([CH3:41])[CH3:42].[Cl:1][c:2]1[cH:3][c:4]([CH:8]2[CH:9]([c:23]3[cH:24][cH:25][c:26]([Cl:29])[cH:27][cH:28]3)[N:10]([CH:15]([C:16](=[O:17])[O:18][CH2:19][CH3:20])[CH2:21][CH3:22])[C:11](=[O:14])[CH2:12][CH2:13]2)[cH:5][cH:6][cH:7]1.[Li+:43]>>[Cl:1][c:2]1[cH:3][c:4]([CH:8]2[CH:9]([c:23]3[cH:24][cH:25][c:26]([Cl:29])[cH:27][cH:28]3)[N:10]([CH:15]([C:16](=[O:17])[O:18][CH2:19][CH3:20])[CH2:21][CH3:22])[C:11](=[O:14])[CH:12]([CH2:32][CH:31]=[CH2:30])[CH2:13]2)[cH:5][cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-320ee5a240b94024a14bd9d9d75b7858
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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