Acetonitrile → tert-butyl N-[3-[(1-ethyl-7-fluoro-2-oxo-3H-indol-5-yl)amino]-2-hydroxypropyl]carbamate
Reaction equation
[C:15]([CH3:16])([CH3:17])([CH3:18])[O:19][C:20]([NH:21][CH2:22][CH:23]1[O:24][CH2:25]1)=[O:26].[CH3:36][C:37]#[N:38].[CH3:39][CH2:40][O:41][C:42](=[O:43])[CH3:44].[F:27][C:28]([F:29])([F:30])[S:31]([O-:32])(=[O:33])=[O:34].[Li+:35].[NH2:1][c:2]1[cH:3][c:4]2[c:8]([c:9]([F:11])[cH:10]1)[N:7]([CH2:12][CH3:13])[C:6](=[O:14])[CH2:5]2>>[NH:1]([c:2]1[cH:3][c:4]2[c:8]([c:9]([F:11])[cH:10]1)[N:7]([CH2:12][CH3:13])[C:6](=[O:14])[CH2:5]2)[CH2:25][CH:23]([CH2:22][NH:21][C:20]([O:19][C:15]([CH3:16])([CH3:17])[CH3:18])=[O:26])[OH:24]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-93fa131e7b624b5bb986e0856b161756
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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