Dimethylformamide → tert-butyl N-[4-[3-[1-(3-methoxypropyl)benzimidazol-2-yl]piperidin-1-yl]-1-naphthalen-2-yl-4-oxobutan-2-yl]carbamate

HRID 2331832Notes

Reaction equation

HRID 2331832 reaction equation
[C:21]([CH3:22])([CH3:23])([CH3:24])[O:25][C:26](=[O:27])[NH:28][CH:29]([CH2:30][C:31](=[O:32])[OH:33])[CH2:34][c:35]1[cH:36][c:37]2[cH:38][cH:39][cH:40][cH:41][c:42]2[cH:43][cH:44]1.[CH3:1][O:2][CH2:3][CH2:4][CH2:5][n:6]1[c:7]([CH:15]2[CH2:16][NH:17][CH2:18][CH2:19][CH2:20]2)[n:8][c:9]2[c:10]1[cH:11][cH:12][cH:13][cH:14]2.[CH3:45][N:46]1[CH2:47][CH2:48][O:49][CH2:50][CH2:51]1.[O:76]=[CH:77][N:78]([CH3:79])[CH3:80].[P-:52]([F:53])([F:54])([F:55])([F:56])([F:57])[F:58].[n:59]1([O:60][C:61]([N:62]([CH3:63])[CH3:64])=[N+:65]([CH3:66])[CH3:67])[c:68]2[n:69][cH:70][cH:71][cH:72][c:73]2[n:74][n:75]1>>[CH3:1][O:2][CH2:3][CH2:4][CH2:5][n:6]1[c:7]([CH:15]2[CH2:16][N:17]([C:31]([CH2:30][CH:29]([NH:28][C:26]([O:25][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:27])[CH2:34][c:35]3[cH:36][c:37]4[cH:38][cH:39][cH:40][cH:41][c:42]4[cH:43][cH:44]3)=[O:32])[CH2:18][CH2:19][CH2:20]2)[n:8][c:9]2[c:10]1[cH:11][cH:12][cH:13][cH:14]2

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 533979213-(Boc-amino)-4-(2-naphthyl)butyric AcidHCID 667850571-(3-Methoxypropyl)-2-piperidin-3-ylbenzimidazole

Product 1

HCID 77190956tert-butyl N-[4-[3-[1-(3-methoxypropyl)benzimidazol-2-yl]piperidin-1-yl]-1-naphthalen-2-yl-4-oxobutan-2-yl]carbamate

Sources & evidence

ORD record
ord-2297456851604565be87dea16c50ed4e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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