Tetrahydrofuran → 5-Bromo-2-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-pyridine

HRID 2332010Notes

Reaction equation

HRID 2332010 reaction equation
[CH2:54]1[O:55][CH2:56][CH2:57][CH2:58]1.[CH3:1][c:2]1[c:3]([CH2:13][OH:14])[c:4](-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[n:5][o:6]1.[O:42]=[C:43]([O:44][CH2:45][CH3:46])[N:47]=[N:48][C:49]([O:50][CH2:51][CH3:52])=[O:53].[OH:15][c:16]1[n:17][cH:18][c:19]([Br:22])[cH:20][cH:21]1.[c:23]1([P:24]([c:25]2[cH:26][cH:27][cH:28][cH:29][cH:30]2)[c:31]2[cH:32][cH:33][cH:34][cH:35][cH:36]2)[cH:37][cH:38][cH:39][cH:40][cH:41]1>>[CH3:1][c:2]1[c:3]([CH2:13][O:14][c:16]2[n:17][cH:18][c:19]([Br:22])[cH:20][cH:21]2)[c:4](-[c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[n:5][o:6]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 2776149(5-Methyl-3-phenyl-1,2-oxazol-4-yl)methanolHCID 178515818HCID 178515818, compound

Product 1

HCID 684448075-Bromo-2-(5-methyl-3-phenyl-isoxazol-4-ylmethoxy)-pyridine

Sources & evidence

ORD record
ord-4500481f30434cfb9afaf19d32adc2f7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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