Tetrahydrofuran → 3-(6-chloro-1-(1,3-dimethoxypropan-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-8-oxa-3-azabicyclo[3.2.1]octane
Reaction equation
[CH3:33][O:34][CH2:35][CH:36]([CH2:37][O:38][CH3:39])[OH:40].[Cl:15][c:16]1[n:17][c:18]([N:25]2[CH2:26][CH:27]3[CH2:28][CH2:29][CH:30]([CH2:31]2)[O:32]3)[c:19]2[c:20]([n:21]1)[nH:22][n:23][cH:24]2.[O:1]=[C:2]([O:3][CH:4]([CH3:5])[CH3:6])[N:7]=[N:8][C:9]([O:10][CH:11]([CH3:12])[CH3:13])=[O:14].[O:60]1[CH2:61][CH2:62][CH2:63][CH2:64]1.[c:41]1([P:42]([c:43]2[cH:44][cH:45][cH:46][cH:47][cH:48]2)[c:49]2[cH:50][cH:51][cH:52][cH:53][cH:54]2)[cH:55][cH:56][cH:57][cH:58][cH:59]1>>[Cl:15][c:16]1[n:17][c:18]([N:25]2[CH2:26][CH:27]3[CH2:28][CH2:29][CH:30]([CH2:31]2)[O:32]3)[c:19]2[c:20]([n:21]1)[n:22]([CH:36]([CH2:35][O:34][CH3:33])[CH2:37][O:38][CH3:39])[n:23][cH:24]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-48f7f3933cb749879b61b95c85c1e9f2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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