Chloride → Methyl 2-chloro-4-(methoxymethyl)-1,3-thiazole-5-carboxylate

HRID 2333027Notes

Reaction equation

HRID 2333027 reaction equation
[CH3:34][C:35]#[N:36].[Cl-:8].[Cl:22][c:23]1[cH:24][c:25]([C:26]([O:27][CH2:28][CH3:29])=[O:30])[nH:31][c:32]1[CH3:33].[N:1]([O:2][C:3]([CH3:4])([CH3:5])[CH3:6])=[O:7].[NH2:9][c:10]1[s:11][c:12]([C:18](=[O:19])[O:20][CH3:21])[c:13]([CH2:15][O:16][CH3:17])[n:14]1>>[c:10]1([Cl:22])[s:11][c:12]([C:18](=[O:19])[O:20][CH3:21])[c:13]([CH2:15][O:16][CH3:17])[n:14]1

Participants

6

Reactant 5

HCID 312ChlorideHCID 6342AcetonitrileHCID 10906Tert-Butyl nitriteHCID 25220423Methyl 2-amino-4-(methoxymethyl)thiazole-5-carboxylateHCID 66707189ethyl 4-chloro-5-methyl-1H-pyrrole-2-carboxylate

Product 1

HCID 45117583Methyl 2-chloro-4-(methoxymethyl)-1,3-thiazole-5-carboxylate

Sources & evidence

ORD record
ord-b42787bead7143e49c3c2db6c773249a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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