Tetrahydrofuran → Temanogrel

HRID 2333526Notes

Reaction equation

HRID 2333526 reaction equation
[CH2:41]1[O:42][CH2:43][CH2:44][CH2:45]1.[CH3:1][n:2]1[n:3][cH:4][cH:5][c:6]1-[c:7]1[cH:8][c:9]([NH2:22])[cH:10][cH:11][c:12]1[O:13][CH2:14][CH2:15][N:16]1[CH2:17][CH2:18][O:19][CH2:20][CH2:21]1.[CH3:23][O:24][c:25]1[cH:26][c:27]([C:28](=[O:29])[Cl:30])[cH:31][cH:32][cH:33]1.[CH3:34][CH2:35][N:36]([CH2:37][CH3:38])[CH2:39][CH3:40]>>[CH3:1][n:2]1[n:3][cH:4][cH:5][c:6]1-[c:7]1[cH:8][c:9]([NH:22][C:28]([c:27]2[cH:26][c:25]([O:24][CH3:23])[cH:33][cH:32][cH:31]2)=[O:29])[cH:10][cH:11][c:12]1[O:13][CH2:14][CH2:15][N:16]1[CH2:17][CH2:18][O:19][CH2:20][CH2:21]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8471TriethylamineHCID 74374m-Anisoyl chlorideHCID 46832486HCID 46832486, compound

Product 1

HCID 11604525Temanogrel

Sources & evidence

ORD record
ord-e5b0e17f82f244658bac8be45143cde3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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