Acetone → 1'-(4-chlorophenyl)-6'-methoxy-5',7',8'-trimethyl-2',4'-dihydro-1'H-spiro[cyclobutane-1,3'-quinolin]-4'-ol
Reaction equation
[BH4-:27].[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[CH3:29][C:30](=[O:31])[CH3:32].[CH3:33][CH2:34][O:35][C:36]([CH3:37])=[O:38].[CH3:44][OH:45].[Cl:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][C:10]3([CH2:11][CH2:12][CH2:13]3)[C:14](=[O:26])[c:15]3[c:16]([CH3:25])[c:17]([O:23][CH3:24])[c:18]([CH3:22])[c:19]([CH3:21])[c:20]32)[cH:6][cH:7]1.[Na+:28]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([N:8]2[CH2:9][C:10]3([CH2:11][CH2:12][CH2:13]3)[CH:14]([OH:26])[c:15]3[c:16]([CH3:25])[c:17]([O:23][CH3:24])[c:18]([CH3:22])[c:19]([CH3:21])[c:20]32)[cH:6][cH:7]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-9bdae29ac7884332ab855f3ca72c66c3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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