Hydrochloric Acid → N-(5-bromo-2-fluorobenzyl)-2,2-dimethoxyacetamide

HRID 2334632Notes

Reaction equation

HRID 2334632 reaction equation
[Br:2][c:3]1[cH:4][cH:5][c:6]([F:11])[c:7]([CH2:8][NH2:9])[cH:10]1.[CH3:12][O:13][CH:14]([C:15](=[O:16])[O:17][CH3:18])[O:19][CH3:20].[CH3:30][OH:31].[CH:21]([N:22]([CH2:23][CH3:24])[CH:25]([CH3:26])[CH3:27])([CH3:28])[CH3:29].[ClH:1]>>[Br:2][c:3]1[cH:4][cH:5][c:6]([F:11])[c:7]([CH2:8][NH:9][C:15]([CH:14]([O:13][CH3:12])[O:19][CH3:20])=[O:16])[cH:10]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 887MethanolHCID 66647Acetic acid, 2,2-dimethoxy-, methyl esterHCID 81531DiisopropylethylamineHCID 2724904(5-Bromo-2-fluorophenyl)methanamine

Product 1

HCID 67520949N-(5-bromo-2-fluorobenzyl)-2,2-dimethoxyacetamide

Sources & evidence

ORD record
ord-0c0bfa8e55d8450a86625f2c0339089f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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