Tetrahydrofuran → 4-{2-[4-(5-Amino-3-tert-butyl-pyrazol-1-yl)-phenoxy]-ethyl}-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:18]([CH3:19])([CH3:20])([CH3:21])[O:22][C:23](=[O:24])[N:25]1[CH2:26][CH2:27][CH:28]([CH2:31][CH2:32][OH:33])[CH2:29][CH2:30]1.[CH2:71]1[O:72][CH2:73][CH2:74][CH2:75]1.[N:34]([C:35]([N:36]1[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41]1)=[O:42])=[N:43][C:44]([N:45]1[CH2:46][CH2:47][CH2:48][CH2:49][CH2:50]1)=[O:51].[NH2:1][c:2]1[cH:3][c:4]([C:14]([CH3:15])([CH3:16])[CH3:17])[n:5][n:6]1-[c:7]1[cH:8][cH:9][c:10]([OH:13])[cH:11][cH:12]1.[c:52]1([P:53]([c:54]2[cH:55][cH:56][cH:57][cH:58][cH:59]2)[c:60]2[cH:61][cH:62][cH:63][cH:64][cH:65]2)[cH:66][cH:67][cH:68][cH:69][cH:70]1>>[NH2:1][c:2]1[cH:3][c:4]([C:14]([CH3:15])([CH3:16])[CH3:17])[n:5][n:6]1-[c:7]1[cH:8][cH:9][c:10]([O:13][CH2:32][CH2:31][CH:28]2[CH2:27][CH2:26][N:25]([C:23]([O:22][C:18]([CH3:19])([CH3:20])[CH3:21])=[O:24])[CH2:30][CH2:29]2)[cH:11][cH:12]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-71cc04ccc9774f65a12d07cc8db0c13a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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