Tetrahydrofuran → Methyl 6-((1-(tert-butoxycarbonyl)pyrrolidin-2-yl)methoxy)-5-chloronicotinate
Reaction equation
[C:13]([CH3:14])([CH3:15])([CH3:16])[O:17][C:18](=[O:19])[N:20]1[CH:21]([CH2:22][OH:23])[CH2:24][CH2:25][CH2:26]1.[CH2:60]1[O:61][CH2:62][CH2:63][CH2:64]1.[Cl:1][c:2]1[c:3]([OH:12])[n:4][cH:5][c:6]([C:8](=[O:9])[O:10][CH3:11])[cH:7]1.[O:46]=[C:47]([O:48][CH:49]([CH3:50])[CH3:51])[N:52]=[N:53][C:54]([O:55][CH:56]([CH3:57])[CH3:58])=[O:59].[c:27]1([P:28]([c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[c:35]2[cH:36][cH:37][cH:38][cH:39][cH:40]2)[cH:41][cH:42][cH:43][cH:44][cH:45]1>>[Cl:1][c:2]1[c:3]([O:12][CH2:22][CH:21]2[N:20]([C:18]([O:17][C:13]([CH3:14])([CH3:15])[CH3:16])=[O:19])[CH2:26][CH2:25][CH2:24]2)[n:4][cH:5][c:6]([C:8](=[O:9])[O:10][CH3:11])[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-f5ba5ff730484f0b916d435331e96e74
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (10/10)
Reaction notes
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