2-Aminothiazole → 6-(Isoquinolin-5-yl)-N-(1,3-thiazol-2-yl)naphthalene-1-carboxamide

HRID 2335074Notes

Reaction equation

HRID 2335074 reaction equation
[CH:30]([N:31]([CH2:32][CH3:33])[CH:34]([CH3:35])[CH3:36])([CH3:37])[CH3:38].[Cl:63][CH:64]([Cl:65])[Cl:66].[NH2:24][c:25]1[s:26][cH:27][cH:28][n:29]1.[P-:39]([F:40])([F:41])([F:42])([F:43])([F:44])[F:45].[cH:1]1[n:2][cH:3][cH:4][c:5]2[c:6](-[c:11]3[cH:12][c:13]4[cH:14][cH:15][cH:16][c:17]([C:21](=[O:22])[OH:23])[c:18]4[cH:19][cH:20]3)[cH:7][cH:8][cH:9][c:10]12.[n:46]1([O:47][C:48]([N:49]([CH3:50])[CH3:51])=[N+:52]([CH3:53])[CH3:54])[c:55]2[n:56][cH:57][cH:58][cH:59][c:60]2[n:61][n:62]1>>[cH:1]1[n:2][cH:3][cH:4][c:5]2[c:6](-[c:11]3[cH:12][c:13]4[cH:14][cH:15][cH:16][c:17]([C:21](=[O:23])[NH:24][c:25]5[s:26][cH:27][cH:28][n:29]5)[c:18]4[cH:19][cH:20]3)[cH:7][cH:8][cH:9][c:10]12

Participants

7

Reactant 6

HCID 21552-AminothiazoleHCID 6212ChloroformHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 58828852HCID 58828852, compound

Product 1

HCID 588288896-(Isoquinolin-5-yl)-N-(1,3-thiazol-2-yl)naphthalene-1-carboxamide

Sources & evidence

ORD record
ord-cc27748d277747478718eeb53c71fdc6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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