Chloride → 1-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-2-phenyl-ethanol

HRID 2336171Notes

Reaction equation

HRID 2336171 reaction equation
[CH2:20]([c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)[Mg+:27].[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[CH3:1][c:2]1[n:3][c:4](-[c:9]2[cH:10][cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[s:5][c:6]1[CH:7]=[O:8].[Cl-:19]>>[CH3:1][c:2]1[n:3][c:4](-[c:9]2[cH:10][cH:11][c:12]([C:15]([F:16])([F:17])[F:18])[cH:13][cH:14]2)[s:5][c:6]1[CH:7]([OH:8])[CH2:20][c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1

Participants

5

Reactant 4

HCID 312ChlorideHCID 8028TetrahydrofuranHCID 27828994-Methyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-5-carbaldehydeHCID 178507042HCID 178507042, compound

Product 1

HCID 210512361-[4-Methyl-2-(4-trifluoromethyl-phenyl)-thiazol-5-yl]-2-phenyl-ethanol

Sources & evidence

ORD record
ord-3d24a2c6286c4b69b6832632469ccb0d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (10/10)

Reaction notes

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